Recovery

Post-Surgical Seroma

Choose a preferred language

Seroma showing surgical incision at surface of skin.

A seroma is a sterile collection of fluid under the skin, usually at the site of a surgical incision. Fluid builds up under the skin where tissue was removed. It may form soon after your surgery. Or it may form up to about 1 to 2 weeks after surgery. It may look like a swollen lump and feel tender or sore.

A small seroma isn't dangerous. Depending on its size and symptoms, it may not need to be treated. The seroma may go away on its own in a few weeks or months. Your body slowly absorbs the fluid. No medicine will make it go away faster. But if you have a large seroma or if it's causing pain, your health care provider may drain it. This is done with a syringe and needle. Or the provider may put in a drain. Seromas can return and may need to be drained multiple times. In some cases, it can become infected or turn into an abscess. In rare cases, you may need a minor procedure to remove the seroma. Long-term problems from a seroma are rare.


Home care

You may be given medicines to relieve pain. These may include acetaminophen and ibuprofen. Take these as directed. Check the seroma daily for the signs of infection listed below.


Follow-up care

Follow up with your health care provider as advised.


When to get medical care

Contact your health care provider right away if you have any of these:

  • Signs of infection:

    • Fever of 100.4°F (38°C) or higher, or as advised by your provider

    • Chills

    • Seroma or skin around it feels warm

    • Pain in the seroma that gets worse

    • Redness or swelling that gets worse

  • Drainage from the seroma that is white, colored, or bloody. Clear or slightly pink fluid leaking is normal.

  • Wound opens up.

  • Fast heart rate.

Call 911

Call 911 if you have any of these:

  • Shortness of breath

  • Trouble breathing

Online Medical Reviewer: Jonas DeMuro MD

Online Medical Reviewer: Raymond Turley Jr PA-C

Online Medical Reviewer: Tara Novick BSN MSN

Date Last Reviewed: 02/01/2025

© 2000-2026 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
heart stethoscope icon

Find a Doctor

Browse our network of pediatric experts.

Find a Doctor
heart cross icon

Departments & Services

Explore specialized care for every need.

View Departments & Services
hospital icon

Find a Location

Find expert pediatric care close to home.

Find a Location
Related Articles
Read article
Surgery
Wound Care After Surgery: Pain

It's normal to feel pain at the incision site. The pain decreases as the wound heals. Pain that continues more than a few weeks after surgery or pain that gets worse any time after surgery can be a sign of a problem.

Read article
Urgent Care
Gunshot Wound

Follow these guidelines to care for your gunshot wound at home.

Read article
Surgery
Wound Check After Surgery, No Complication

If your wound was sewn closed, you shouldn't have to change the dressing more than twice a day in the first few days. Follow these home care instructions after your wound check.

Read article
Ear, Nose, and Throat
After Endoscopic Sinus Surgery

Learn what to expect as you recover in the weeks after your endoscopic sinus surgery.